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enough to admit the end of the little linger. There was some
blood infiltrated in the areolar tissue beneath the artery, and
the peritoneal cavity contained a large quantity of blood. stromectol for lice
The specimen was of no particular interest, except from the
fact that it occurred in a patient who had syphilis, and that,
in all probability, there was a certain amount of hsemorrhage
from rupture before he was admitted into the hospital, which
haemorrhage was arrested by temporary coagulation. The in-
ternal coat of the artery was lined with atheromatous deposits.
The patient was thirty-seven years of age.
De. scabies stromectol Jais'eway believed that syphilis was not only a very
common cause stromectol for scabies of aneurism, but also of valvular disease. He
had met with two cases of thickening of the valves which
could be explained in no other way.
Dr. Flint had not had his attention drawn particularly cheap stromectol to
syphilis as a cause of valvular disease, but thought that it
might explain many ivermectin stromectol of the cases of the latter lesion, in which
none of the usual causes were made out.
De. Mason had seen several cases of aneurism which ap-
peared to be the direct result of constitutional syphilis. lie
referred to one case in point, occurring in a stromectol uk man aged thirty-
three.
Dr. Looivns alluded to a long list of stromectol online cases published within
the last two years in the Lancet^ in which all under the age
of forty gave a syphilitic history.
De. Kogees w\as order stromectol online reminded of a case presented to the Society
ten years ago, of very extensive aortic disease, in a young man
twenty-eight years of age, who had contracted syphilis only
eighteen months before his death. The patient eventually
died of extensive aortic stromectol canada disease. In that case no other cause
for the arterial and cardiac lesions was assigned than sypliilis.
Physiological and Therapeutical Action of Quinine. stromectol buy — The fol-
lowing is a summary of the results of recent investigations on
556 MISCELLAISTEOUS AND SCIENTIFIC NOTES.
tills subject by Binz, Eanke, Kerner, Schulte, Zuntz, and
Scharrenbroich :
Binz finds that quinine has the power of arresting the pro-
cesses of putrefaction and fermentation in generic stromectol a high degree, and
that it is an active poison for all low organisms, aniii^l and
vegetable. According to Cohnheim's \news, pus being mainly
a collection of white blood -globules, which have passed through
the walls of the vessels — further, quinine having the power of
arresting the motions of the white corpuscles, and hence pre-
venting their exit from the vessels — stromectol price the alkaloid arrests, or at
all events diminishes, the formation of pus during the course
of inflammation. Moreover, it destroys the ozonizing power
of certain substances ; buy stromectol online and, a"s the red corpuscles have this
power, quinine in the blood probably diminishes oxidation of
tissue, and lessens the production of heat. Eanke and Kerner,
indeed, have found that quinine in large doses diminishes tis-
sue-changes, as is shown by the smaller quantities of urea and
uric acid excreted buy ivermectin ; and there are many observations to show buy cheap ivermectin
that in fevers it produces a decrement in temperature. Ranke
and Kerner's experiments do not show, however, how far the
lessening of tissue-waste is due to the direct action of quinine
on oxidation, and how far to the indirect action of the alkaloid
through the nervous system. Two methods have been em-
ployed for ascertaining the stromectol 3 mg direct influence of quinine on oxida-
tion. Ilarley added quinine to the blood, and found that this,
when so treated, took up less oxygen, and gave off less car-
bonic acid, than blood which had not been so treated. This
method is inconvenient of application, and liable to error. order stromectol
Zuntz emploj^ed the changes in the alkalinity of the blood for
arriving at the same results. Schulte has extended these re-
searches. If fresh blood be drawn, a development of acid
begins in it, and continues, at first rapidly, then more slowly,
till putrefaction sets in. Of course this acidification depends
on oxidations; and the diminished alkalinity of the blood,
thereby produced, furnishes buy cheap stromectol a test of the rapidity with which
oxidation proceeds. Schulte has confirmed the observation
first made by Zuntz and Scharrenbroich, that quinine and
berberine lessen the production of acid. Harley's observation
is thus confirmed. Cinchonine produces similar results to
quinine, though in a very inferior degree. Picrate of sodium
is nearly as powerful as quinine. Zuntz found, as Eanke and
Kerner'had previously done, that quinine in ten-grain doses
lessens the daily excretion of urea by one-third or more. Un-
ruh has found the same to occur when quinine is administered
in fevers; but his observations are open to objection. Binz's
experiments are curious, and show that, when putrefying
MISCELLAKEOUS AIS'D SCZElSTrFIC NOTES. 557
liquids are injected into the circulation, the temperature of the
body rises ; but, stromectol purchase if the fluids be previously mixed with quinine,
whereby the putrefactive processes are arrested or destroyed,
the rise in temperature is either entirely arrested or consider-
ably diminished.
Mental Influence in Disease. — Prof. Austin Flint, in an arti-
cle in the American Practitioner for January, 18Y2, on the
agency of the mind in etiology, prophylaxis, and tlierapeutics,
says :
We meet sometimes with cases in which recovery from
disease seems fairly attributable, in a great measure, to a
resolute determination on the j)art of the patient to recover.
An unfavorable prognosis is communicated to a patient. He
declares that he will not die, and he gets well, wlien, accord-
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