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of these schools, which, we understand, are the first
of their kind to have been established.
THE Order Renova SUPPOSED MICRO-ORGANISM OF SYPHILIS.
Dr. Justin D. Lisle, an Renova Price American physician who,
as he informs us, has been for nearly three years on
the laboratory staff of the Institut Pasteur, has sent
us a copy of a communication presented before the
French Academy Renova Prices of Medicine on July 2d by himself
and Dr. Louis Jullien, who is the surgeon of the St.-
July 27, Ipoi.]
EDITORIAL ARTICLES.
167
Lazare prison for prostitutes. The substance of the
communication is as follows :
Although the blood of syphilitic persons has often
been found sterile from the bacteriological point of
view, the authors, in their quest for the germ Order Requip of
syphilis, decided to make that liquid the subject of
their studies, because it seemed to them impossible
that it Renova Coupon should not contain, free from all impurity,
the agent that infected all parts of the organism,
and they selected cases of recent infection that had
not been subjected to specific treatment. Buy Renova Online Drawing
blood directly from a vein, they examined it at once
and also its serum. They observed the presence of a
round, granular, highly refractive body capable of
traversing the Chamberland filter and endowed with
a mobility that was perhaps Brownian. Such bodies
had been seen before by other observers, but neither
in cultures nor in inoculations upon animals had
they ever given any result. Remembering that the
coagulated blood of syphilitic Cheap Requip subjects did not Renova Buy con-
vey the disease, they were not surprised at this fact.
They accounted for it by assuming the presence in
the serum Purchase Renova of a highly bactericidal body, an alexin.
To avoid the formation of this substance, they per-
formed their experiments with the plasma and with
the contents Buy Renova of blisters.
The organism which they found they describe as
polymorphous, its appearance varying from that of
a short bacillus to that of a very long filament, Renova Cream with Price Of Renova
the extremities vaguely rounded but not swollen
into a hammer shape, moving freely under the micro-
scope. It takes all the usual stains well, but it must
not be dried in a flame or at a temperature above
140° F. It is well to treat it with alcohol and ether,
with a solution of osmic acid, or with a saturated
aqueous solution of corrosive sublimate to which
acetic acid has been added. It does Renova Cost not take the
Gram stain.
Bouillon inoculated with it becomes turbid in
twenty-four hours, and in four or five days there is
formed a light pellicle which does not extend or
become thickened. It slowly liquefies gelatin, and
the liquid becomes cloudy and flocculent and as-
sumes a greenish hue. The gelatin is not colored,
and its surface remains even. On ordinary gelose
and on glycerinated and peptonized gelose it gives
rise to a creamy coat which Requip Mg is always moist and of
a very slight greenish tinge. It grows Buy Requip Online very well on
glycerinated potato, in the form of a whitish layer,
neither dry nor Cost Of Renova scaly, which collects in the bottom of
the tube. It grows invisibly and without liquefac-
tion on solid serum and abundantly on liquor amnii,
and it grows very Purchase Requip well on media inoculated with
pyocyaneous or colon-bacillus cultures. It does not
coagulate milk, but precipitates the casein, leaving a
fatty layer at the surface; the reaction Renova Online is alkaline.
Its anaerobic development is slow. It never pro-
duces pyocyanine or indol. Most of the cultures
have a stale, disagreeable odor, but are not foetid.
Passing over the modifications described by the
authors as occurring in the germ on its cultivation,
we come to their inoculation experiments. Cultures
injected into the peritonaeum of the guinea-pig gave
rise to paralysis, emaciation, abortion, and death in
from ten to fifteen days. Young guinea-pigs were
killed by the procedure in twelve hours. Injected
subcutaneously, the cultures cause loss of hair and
the formation of an indurated and ulcerated patch,
with engorgement of the neighboring lymphatic
glands. Post mortem, the urine is found albumi-
nous, the spleen is contracted, sometimes the kidneys
and the liver show fatty degeneration, and the blood
is always sterile. In Buy Requip frogs the effects are most
striking, and death occurs in thirty-six hours. The
fact that the dead bodies of all the animals were ster-
ile led the authors to make an investigation as to
whether or not the same state of things was the case
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