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urine caused the entire series of symptoms which we are ac-
customed to attribute to urine in general. He then experi-
mented to find generic lexapro price drop out the length of time required for acid urine
in contact with animal tissues to become alkaline. iN'o alka-
line reaction was developed earlier than the fifth day, and usu-
ally not before the tenth. discount lexapro He then inquired if acid urine, re-
maining for a long time in contact with the tissues of the body,
would not act injuriously, without undergoing decomposition.
His experiments enabled him to answer this inquuy in the
negative. Lastly, it remained to find out how to account for
the sloughing which takes place in the human subject so
quickly, and over so great an extent of surface, after infiltra-
tion of urine, lexapro price per pill which is without doubt acid. This sloughing is
not produced by any injurioris properties of the acid urine, but
is the result of a purely mechanical cause, viz., the pressure
exerted by the extra vasated fluid upon the tissues.
From his experiments he decides that it is unnecessary, in
operations for fistulas, etc., to devote so much care to keep
the surfaces of the wounds from contact with urine, and that
the use of the catheter may be dispensed with in the after-
treatment. In cases wliere, from cystitis, or other cause, the
urine is alkaline, this condition should be obviated before op
crating, or else the greatest attention must be given to preven
420 MISCELLANEOUS A2fD SCIE^^TIFIC ITOTES.
the urine touching the denuded surfaces. The proper treat-
ment buy discount lexapro for " infiltration of urine " is, to leave the ah'eady extrav-
asated fluid to take care of itself (it will be absorbed), and,
in order to prevent further infiltration, to open the urethra
through the perinceum, and introduce a catheter through the
wound into the bladder and leave it there.
Simon is satisfied, from his experiments with saliva upon
the surfaces of wounds, that no one need at any time hesitate
to operate within the buccal cavity, through fear of failui-e to
obtain union from the injurious effects of the saliva ; and, fur-
ther, that when the operation does not succeed, we must look
for the cause of failure elsewhere than to the saliva.
Inflammation of the Vascular Walls. [Durante, Med. Jahrb.,
ISYl, 3 cheap lexapro alternative H.] — In average cost generic lexapro order to prove the physiological relation of
the ;iutrition of the coats of the vessels, especially of the non-
vascula intima in rabbits, the vena jugularis was ligated with-
out injuring its sheath, at first peripherically, and then, after
ligation of all the lateral branches, centrally, in order to empty
the venous trunk of blood ; and on the carotid, the same oper-
ation was performed in an opposite manner.
The examination, forty-eight hours after, showed that,
in the neighborhood of the ligatures, all the layers of the
vessels were studded with pus-globules ; at a little distance
from the ligatures, however, no striking change had occurred.
In a second series of experiments, the vena jug. et art. carot.
were exposed and removed by isolation from the nutritive
influence ; the current of blood, however, was not interrupted.
Fifty-two hours discount lexapro online after, the examination showed that the vas-
cular walls were more or less changed. The lexapro price comparison inner surface
was opaqne ; the endothelium of the veins partly destroyed,
partly displaced by rounded cells. Small prominences on the
inner surface proved to be coagula. The muscular tissue of discount lexapro card the
artery, whose endothelium was better preserved, appeared as
if macerated ; the corpuscles of the get discount lexapro muscular fibres were
angular, and at times broken in pieces. In five cases the
necrosis extended twice as far as the intima. From these
experiments the author deduces that the intima does not
receive sufficient nutritive material immediately from the
MISCELLA^S'EOUS AND SCIEXTIFIC NOTES. 421
circulating blood, but that especially in tlie veins it is nour-
ished discount lexapro no prescription by diffusion of the fluids discount lexapro coupons which cheap lexapro no prescription the other coats furnish.
By cauterization of the exposed, cheap lexapro canada veins by the actual cautery
(still better when the peripheric ligation was pi'eviously
undertaken) the author was able to demonstrate in twenty-
four to fifty-six hours, generally by the use of the chloride
of gold or the nitrate of silver, changes in the intinia, which
consisted, on the one hand, of an increase of the intercellular
substance in the entire periphery of the endothelium, and in
the other, of an increase of corpuscles prescription discount lexapro in the endothelium, a
granulation of the same, and a partial change into fibres.
The examination of veins, altered in various ways by inflam-
mation, presented also a reaction in the smooth muscular
fibres, whose nuclei took on proliferation, and whose corpuscles
even were divided into small sections, so that the author, as
regards the venous walls, asserts that " the cheap lexapro online endothelium,
muscular cells, and connective-tissue corpuscles take part in
the proliferation."
In order to throw light upon the relations between the
intima and the blood in the occluded venous sacs, the
vena jugularis of rabbits was compressed by the insertion of
insect-pins and a ligature, without direct injury to the coats
of the vein. The examination, thirty-six to forty-eight hours
after, showed that the blood in the occluded veiai remained
fluid as long as the endothelium had not received inflam-
matorv chano-es throuirh the mechanical irritation of the
needles ; and that, further, the coagulation of the blood went
hand in hand with lexapro discount program a change in the endothelium. From
these observations the author assumes that the fluidity of
the blood in occluded vessels is dependent upon the normal
functions of the vascular walls.
On lexapro price Polypus of lexapro price generic tiie Rectum in Children. {Jahrl. f. Klnder-
TcmnMi., 4. II., 1871.) — Prof. Bokay met with 25 cases of rec-
tal polypus in 65,9Y0 sick children. One of these polypi,
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