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the results of this in phenomena appreciable to tlie individual. estrace coupons
Thus, the lassitude felt after the warm bath may be attributed
to imperfect nutrition of the muscles from the insufficient sup-
ply of blood to them resulting from this action. The tendency
to syncope produced by the protracted use of the warm bath
is probably owing to the diminished supply of blood to the
brain, caused by the increased facility for its passage through
the capillaries of the skin. On the same principle, the wake-
fulness of insanity may sometimes be overcome by hot appli-
cations to the chest and abdomen.
The converse of this is observed in the vigor which results
from the use of the cold bath, or from exposure to a cold and
bracing atmosphere. Here we have the vessels of the skin
reduced in calibre, and as a consequence a greater proportion
of the blood sent out by each contraction of the estrace cream coupon heart is com-
pelled to find its way to the veins through the capillaries of
the muscular and nervous systems.
But, under certain conditions not well understood, an im-
pression of cold upon the surface leads buy estrace to such a diminution
in the cutaneous circulation, and consequently to estrace 2 mg such a dis-
tention of the visceral capillaries, as to induce a lesion of some
one or more of the viscera. The pneumonia, bronchitis, ne-
phritis, or diarrhoea, as the case may be, is then said to be the
result of " taking cold." If in tlie very earliest stage the warm
bath or some internal sudorific be resorted to, and a free chan-
nel thus opened in the estrace 2mg skin for the passage of blood, the inter-
nal organ maybe relieved, and the threatened disease averted.
But an impression of cold upon the surface may, under
some circumstances, prove salutary. Thus, in syncope, we
CIECULATION OF THE BLOOD. 349
dash cold water into the face and ui^on the chest, in order, as
we say, to rouse the system by the sudden shock. Tlie shock
may perhaps have something to do with the result, but we do
not find other means of rousing the nervous system to be
equally efiicacious. Shaking, flagellation, etc., so useful in
opium-poisoning, do not approve themselves to ns in this case.
But cold water, combining with the shock a sudden contrac-
tion of the cutaneous vessels, and thus forcing more blood
into the internal organs, including the nerve-centres, is an agent
which has been used from time immemorial with success.
Medicines estrace ivf which are supposed to have a certain degree of
control over the diameter of the capillaries are described in
works on materia medica, and not estrace 1 mg unfrequently prescribed in
cases in which the design is to affect the circulation in some
diseased locality through the general action of the drug. The
reasoning is as follows : " This medicine acts upon tlie capilla-
ries — tlie capillaries in the diseased organ require such action
— ergo^ the medicine is indicated." ISTow, if the diseased part
is supposed to be acted upon only as a j^ortion of estrace for ivf the general
organism, and not from any special relation to the medicine,
the employment of tlie latter must result in disappointment,
for the simple reason that, if all the capillaries of the body are
acted upon alike, no change in the distribution of the blood
will ensue. The most that, can happen is, that the labor of
the heart will be increased or diminished. The same result
would be attained by employing a cardiac sedative estrace cream or a car-
diac stimulant.
These remarks will apply to the use of opium and of ergot
as antiphlogistics. I do not intend to raise a question as to
their efficacy for this purpose, but merely to attack the theory
of their suiDposed mode of action, which I believe to estrace estradiol be buy estrace online un-
tenable ; unless, indeed, it can be shown that the capillaries of
inflamed parts are peculiarly sensitive to their influence.
Closely allied to this subject is one which has recently as-
sumed especial importance in connection with a new method
of laying the foundations of piers for bridges. I refer to the
physiological and pathological eSects of high atmospheric
pressure.
In constructing the piers for the bridge across the Missis-
sippi at St. Louis, in 1869, a novel plan was adopted for reach-
350 CIRCULA.TIO]^ OF THE BLOOD.
ing tlie rock below the bed of tbe river. An immense estrace online diving-
bell was constructed, having the horizontal dimensions of the
proposed pier. This was smik down to the bed of the stream,
and upon its top was built the buy estrace cream masonry of the pier. The in-
terior of the bell — or caisson, as it was termed — was kept
clear of water in the usual manner, by forcing in air through
pipes leading from pumps located on the shore. Excava-
tion was carried on within the caisson, the earth being re-
moved estrace tablets through a sliaft in such a way as not to permit the
escape of air. As the work progressed, the caisson was con-
stantly sinking into the earth, while the masonry above was
being built up in the same proportion, so as always to keep
the top of the pier above the surface of the water. In this
way, the earth estrace and ivf being removed from beneath and the stone
being added above, estrace cost the vast structure, having in the case of
one of the piers an area of thirty-six hundred square feet, estrace price was
carried estrace creme down to a depth of one hundred and ten feet, when it
rested upon solid rock. The interior of the caisson was then
filled up with concrete, and a perfectly solid foundation for
the pier was secured.
Of course, in proportion as the caisson descended, the press-
m'e of the air required to keep out the water constantly in-
creased, until estrace coupon at last it attained the enormous figure of fifty-
five pounds to the square inch in excess of the normal rate, a
pressure nearly equal to the maximum capacity for resistance
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