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Dr. Michael Foster has investigated the physiological properties of
the dei'ivatives of codeia. As we have given an account of their chemical
properties as stated in Prof. Wright's paper, we corai^lete the subject by Buy Acticin
noting some of Dr. Foster's experiments:
The hydrochlorate of clilorotetracodeia, and the hydrobromate of
bromotetraraorphia, in doses of a decigramme by subcutaneous injection
or by the mouth, produced in adult cats in a very few minutes a condition
of great excitement, almost amounting to delirium, accompanied by a
copious flow of saliva and great dilatation of the pupils. Micturition and
defecation occurred in some instances, and vomiting was observed on two
occasions with the morphia-salt, but was very slight. The excitement was
very peculiar, being apparently due partly to increased sensitiveness to
noises, and partly to an impulse to rush about.
The same doses of the morphia- salt given to a young kitten produced
the same flow of saliva, dilatation of pupils, and excitement (without
vomiting); but the stage of excitement, which in adult cats passed grad-
ually otf in a few hours, was followed by a Purchase Acticin condition marked by a want
of coordination of muscular movements, and presenting the most grotesque
resemblance to certain stages of alcoholic intoxication. This stage was
followed in turn by sleepiness and stupor, in which the kitten was left at Purchase Acticin Online
night; in the morning it was found dead.
Two observations have shown that these salts pai'alyze (in dogs and cats)
the inhibitory fibres of the pneumogastric; they also seem to lower the
internal tension, but Acticin Cream 5 want of material has prevented from ascertaining
how tliis is brought about. Acticin Price
On rcibMts neitlier salt, even in doses of a decigramme, seems to have
any effect, except jjerhaps a slight excitement. There is no dilatation of
the pupils, no flow of saliva, and, if one observation can be trusted, no
paralysis of the inhibitory fibres of the pneumogastric.
No Acticin Cream marked difference was observable between the two salts, except
that the Buy Acticin Online morphia Generic Acticin salts seemed rather more potent than the corresponding
codeia bodies.
The salts of deoxycodeia and deoxymorphia given by mouth or by sub-
cutaneous injection, in doses of a decigramme, produced in adult cats,
almost immediately after exhibition, a series of convulsions much more
epileptic in character than tetanic. In one case there was a distinct ro-
tatory movement. In a few minutes these convulsions passed away, leaving
the animal exhausted and frightened. Then followed a state of excitement,
with dilated pupils and flow of saliva, very similar to the eflects of the te-
tracodeia and tetramorphia salts, but less marked.
MISCELLANEOUS AND SCIENTIFIC NOTES. 211
P^isallaiTcous mib- Smnitftc Jot^s.
Billroth on Acupressure, Acutorsion, and Torsion. — In Hfty
cases of amputation Prof. Billroth performed acupressure or
acutorsion, using on an average four needles in each case; he
has perfoj-med it on two hundred arteries, including fifteen
cases of amputation of the thigh ; he has had no opportunity
in cases of amputation of hip-joint, having had no cases lately ;
in Order Acticin Online exarticulation of shoulder he never succeeded in fixino- the
needles firmly enough to rely on methods ahove named.
Acutorsion was performed more, acupressure less frequently,
acufilapressure in no case. Hsemorrhage following removal
of needles occurred in one case only ; he accounts for it by his
having performed acupressure according to the first English
method, compressing against the integument, the brachial
artery, the median nerve, and belly of the biceps muscle ; this
caused fluxion to the compressed parts ; removing the needle,
they receded, tearing the adhesions which had compressed the
artery. He therefore abstains from acupressure Acticin Permethrin Cream en masse, and
recommends careful acutorsion. In acutorsion, he considers
one half turn sufiicient, and preferable to a whole turn or
more, since the needle is removed more readily. Gold needles
occasionally become bent if very long ; but they can be re-
moved without causing irritation, and are therefore preferable
to all others.
Prof, Billroth attempted torsion in several cases of amputa-
tion of the breast, with such negative results that he abstained
from it until again led to it by English surgeons, and Porta,
who performed it four hundred times without secondary
haemorrhage (out of twenty-three attempts of torsion of the
femoral artery he failed four times, and applied ligatures).
During last summer Billroth performed torsion in five am-
putations of the leg, two of the foot, two of the fore, and one
of the upper arm ; also upon the greater number of arteries in
several amputations of the thigh.
Secondary haemorrhage occurred in one case, from the pos-
terior tibial ; he believes this was due to his having forced the
torsion. To perform torsion successfully, he considers it neces-
212 MISCELLANEOUS AND SCIENTIFIC NOTES.
sary — 1. To isolate the vessel tlioroughly ; 2. To Buy Cheap Acticin grasp the
end of the same with a strong, well-fitting pinzette ; 3. There
must be a certain length of vessel from the end to the nearest
branch. These conditions are not given in the mammse, hence
his previous failure.
Although Porta recommends making but slight traction, Order Acticin
four to five turns in small, and six to eight in large vessels,
Billroth has in every case drawn out the vessel from one to
one and a half inch, and turned the pincers until the vessel
was torn asunder, one portion remaining in the instrument,
the other receding ; this was done to alter the walls as much
and as far as possible, in order to gain an extensive thrombus.
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